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ADVANTAGES
LIMITATIONS OF CONVENTIONAL THERAPEUTICS
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Poor water solubility
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Tendency to aggregate
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Non-specific/non-local biodistribution
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Systemic toxicity
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Low therapeutic index, high drug dose
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Multi-drug resistance
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Susceptible to physiological degradation
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Repeated administration necessary
ATTRACTIVE PROPERTIES OF POROUS SILICON
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Large surface area to volume ratio
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The outer surface can be functionalized/modified
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Tunable size and shape
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Customizable surface chemistry
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Biocompatible and biodegradable
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Stabilization of API
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Photoluminescence

ADVANTAGES OF RAMPORSIL DELIVERY SYSTEM
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Increased treatment efficacy
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Dosage localization
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Decreased toxic side effects
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Reduced dose
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Controlled biodistribution
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Modulated pharmacokinetics
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